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Claude Fable 5
2622 points | 2154 comments

macOS Container Machines
1266 points | 434 comments

If Claude Fable stops helping you, you'll never know
1035 points | 500 comments

CRISPR tech selectively shreds cancer cells, including "undruggable" cancers
991 points | 219 comments

Noise infusion banned from statistical products published by Census Bureau
891 points | 592 comments

CEOs who think AI replaces their employees are just bad CEOs
842 points | 309 comments

Ask HN: Has anyone replaced Claude/GPT with a local model for daily coding?
810 points | 381 comments